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(13) The murine models were divided into six groups, where the control group was presented with a placebo and the rest with DSIP
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Futhermore, 1,25(OH)2D3 has been demonstrated to reduce the expression of matrix metalloproteinase-9 (MMP-9), which plays a crucial role in degrading extracellular matrix components, including collagen, fibronectin, and laminin, as well as tight junction proteins, leading to BBB instability [106]
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